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KMID : 0370220220660060303
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Yakhak Hoeji
2022 Volume.66 No. 6 p.303 ~ p.307
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Study on Blood Cholesterol Improvement Functionality of Bifidobacterium breve IDCC 4401 Heat Treatment Culture Powder, a Health Functional Ingredient
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Kim Min-Cheol
Kim Min-Goo
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Abstract
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Blood cholesterol is an item of national health examinations in Korea, which is one of the essential healthindicators that healthy and semi-healthy people, who are not in the stage of taking medicine, also need to be managed bycontrolling their lifestyle. HMG-CoA reductase inhibitors, which are commonly used to lower blood cholesterol, have beenreported to have various adverse events, and there are several factors limiting their application. As a result, semi-healthyand healthy people who do not have critical health issues may not be able to take these drugs. Bifidobacterium breveIDCC 4401 heat treatment culture powder (BBR4401) is a functional raw material obtained by heat-treating and killingthe probiotic Bifidobacterium breve which is widely used as a functional raw material for improving intestinal health infoods and health functional foods. In addition, BBR4401 is a raw material with safety and stability which has beenrecognized for its cholesterol-improving functionality. Therefore, healthy and semi-healthy people who wish to managetheir blood cholesterol can consume BBR4401 for prevention/management purposes. Furthermore, BBR4401 has anentirely different mechanism of action from HMG-CoA reductase inhibitors in that it inhibits the reabsorption ofcholesterol/bile acids in the small intestine, meaning that even those who are taking HMG-CoA reductase inhibitors canconsume BBR4401 to manage their blood cholesterol; this treatment combination is expected to provide a synergic effectin improving cholesterol.
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KEYWORD
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Bifidobacterium breve IDCC 4401 heat treatment culture powder, Bifidobacterium breve, Cholesterol, Bile acid, Health functional food
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